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Q. 18 - Which medications actually taken for COVID-19?

 

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This question was skipped by 6 respondents. The same 6 ptovided no date of diagnosis, and reported having had no positive test.

 

Q

 

These are medications actually taken during the course of illness, as preseumed therapy for COVID-19 or possibly, complications of that illness. One thinks of secondary bacterial infections after a viral illness. The indications and potential complications of some of the ones most commonly taken should be noted. 

 

Ibuprofen may be of use in preventing lung damage. It's use in those severely ill, where it neither improved nor worsened mortality and respiratory status, does not reflect this population of respondents who overwelmingly have a moderate illness severity. A useful review is presented here

 

Antibiotics have no effect on viral illness. Co-infections or secondary bacterial infections may indicate use of antibiotics. They are rare in the COVID-19 population. How many of our respondents had proven secondary infections is unknown at this time. But specifically, antibiotics in the setting of COVID-19 are greatly overused and usually not indicated in both virally infected adults and children.

 

Prednisone : An early short course of methylprednisolone in hospialized patients with moderate to severe COVID-19 reduced escalation of care and improved clinical outcomes. Most respondents (81.5%) to our questionnaire were never hospitalized. Those with less severe disease have not insignificant risks, and probably little benefit demonstrated so far. A "why not try it" attitude with Prednisone is probably not indicated, and based on unacceptable indications as reviewed here. Instant gratification, on both sides of the needle, is not or should not be taken as an appropriate indication for this medicaion.

 

In our respondent sample: 92 (68.15%) were never hospitalized;

 

12 (8.89%) were hospitalized 1 day or less;

13 (9.63%) were hospitalized more than 1 day.

Total hospitalizations for greater than 1 day, lasted 94 days total for these 14 respondents, each for a mean of 7.23±6.00 days.

 

In this last group of 14 respondents (> 1 day in hospital), 5 (35.71%) felt they had a moderate illness, 7 (50%) a severe illness, and 2 (14.29%) a critical illness.

In this last group of 14, 5 received ibuprofen, 4 received antibiotics, and 4 received prednisone.

 

This suggests that ibuprofen, antibiotics and prednisone were used appropriately in 4 or 5 of the 28 to 51 times that they were actually given.

 

 

It is difficult to judge clinical decisions if one is not present when they are taken.

 

 

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07/11/2020
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